Day 1 :
Keynote Forum
James D. Bates
American board-certified oral and maxillofacial surgeon, USA
Keynote: Diagnosis, Nonsurgical and Surgical Treatment of Obstructive Sleep Apnea
Time : 55ew6

Biography:
James D. Bates, D.D.S., M.D., is an American board-certified oral and maxillofacial surgeon in active private practice in Dallas, Texas. Originally from Lubbock, Texas, he attended Texas Tech University as an undergraduate. He graduated with many honors from The University of Texas Dental Branch at Houston with a D.D.S. degree, and from Texas Tech University School of Medicine with an M.D. degree. In addition, he completed an internship in general surgery at Baylor University Medical Center and completed an accredited residency in oral and maxillofacial surgery at The University of Texas Health Science Center in Houston. As a part-time faculty member at Texas A&M Baylor College of Dentistry in the Department of Oral and Maxillofacial Surgery, he taught physical examination and internal medicine to graduate students in all specialties as a Clinical Associate Professor for 18 years. As the founder of Texas Oral and Maxillofacial Surgery, his practice is proud to have maintained 12 years of continuous accreditation as an Office-Based Surgery Practice by the internationally-recognized Joint Commission. His practice focuses on providing full-scope oral and maxillofacial surgery services including orthognathic and TMJ surgery.
Abstract:
Sleep-disordered breathing is a hot topic in dentistry and medicine today. Dentists are in a unique position to screen for, diagnose and treat their patients with obstructive sleep apnea. OSA is a serious, potentially life-threatening condition which can result in hypertension, congestive heart failure and even death. This presentation will cover the screening, diagnosis and contemporary management of sleep-disordered
breathing in a comprehensive format, both for the general restorative dentist, the orthodontist and the oral and maxillofacial surgical specialists. From the medical history and clinical examination, to radiographic and diagnostic imaging findings, to a detailed discussion of the clinical polysomnogram and sleep medicine consultation referral, to mandibular advancement oral appliance therapy and CPAP therapy, to upper airway surgery including uvulopalatopharyngoplasty (UPPP), laser-assisted uvuloplasty (LAUP), nasal septoplasty, inferior turbinectomy, tonsillectomy and adenoidectomy, radiofrequency tongue and soft palate ablation, to maxillomandibular advancement and genioglossus advancement, to tongue and hyoid suspension, this presentation will provide direct and practical real life ways to improve the health and prolong the life of your patients with maximal fulfillment in return.
Keynote Forum
Oscar Malaguti
Mr. Face Odontostomatological Clinic, Italy
Keynote: Sleep Dentist
Time : 5665r

Biography:
Degree in Dentistry and Dental Prosthetics University of Perugia with 110/110 cum laude. Degree in dental technician in Pesaro. Collaboration with Prof. T. Testori for maxillary sinus surgery and immediate loading in large rehabilitations. Tutor of surgery and periodontology. He followed Prof. G. Zucchelli as second operator, learning gingival mucus surgery and regenerative periodontal surgery. Tutor for cadaver dissection courses at the Institut de Formation en Implantoligie Université in Paris and at the Institute of Anatomy of the University of Vienna. Collaboration in orthodontics and minimally invasive orthognathic surgery and maxillary and mandibular segmental corticotomy. She attends the courses on prosthetics on natural teeth and implants by Dr. I. Loi and Dr. M. Fradeani. Master II level at the University of Padova in “Analgesic Sedation and emergencies in odontostomatology" by Prof. G. Manani. 1st level Master's degree at the University of Torino in "Pathogenic odontostomatological pathologies". Specialized Degree at the University of Torino in "Orthognathic Surgery and Facial Malformations" Prof. G. Ramieri. He holds courses in basic and advanced implant surgery and sedo-analgesia together with the Kristal Reserch group in Bucharest and in Italy. Masters in Sleep Dentistry at the University of Bologna
Abstract:
The importance of the role of the dentist today is of great importance for the concepts that can be learned and obtained from the study of sleep and the knowledge of the patient's medical information. Today, the dentist spends a lot of time with the patient and is able through communication, motivation, encouragement, to improve the quality of life for a long time. The dentist's medical team must also think about the general health necessary for every patient to face life in the best possible way.Now in our work we are the coaches of our patients and we must be able to motivate, encourage, direct and assist their changes and see how our role gains importance in the patient's psychophysical health processes.The dentist's duty is to investigate and treat in addition to oral hygiene, nutrition, physical and mental health, encouraging the patient in this direction because it is and will be the direction of future health of people.
Keynote Forum
Eren Cicek
University of Copenhagen, Denmark
Keynote: The versatile indications, techniques and properties of composites: different approaches to day-to-day-cases with silicone based indirect restorations and nanohybrides!
Time : 576

Biography:
Before Dr.Eren Cicek graduated from the University of Copenhagen, Denmark in 2015, he had tutored and lectured medical,- and dental students at the faculty of health and medical sciences in the aforementioned University. Since then he's been working in a private clinic, focusing on endodontics,- and restorative dentistry. In a period of 6 months he also worked as a pedodontist, mainly focusing on syrian refugee children, in relation to the massive immigration that Denmark had in the early 2016. He keeps lectures several times a year on various topics.
In Autumn 2016 he became the owner of the clinic that had him employed, in Copenhagen. Since then he's been conducting all sorts of dental treatments. Most recently he has returned from Germany, Cuxhaven, lecturing at the VOCO international fellow symposium and Oslo from lecturing in composites.
Abstract:
My presentation deals with the versatility of composites (types and techniques), its many functions and indications. Composites is a well known, and well used material in every dental practice, all over the world. Its properties varies from being colorstable, flexible, elastomeric and resistant to incoming forces. The latest trend in the ever growing universe of composites is nano-hybrid composites, which is also entirely biocompatible. These are just few of many of the advantages of composites, which dentists are enjoying from their day-to-day work. Before the clinical cases, the subject of light curing is going to be mentioned briefly, as it is imperative for the clinician to excecute properly, this phase properly, for sufficient restorations on patients.
With a solid theoretical foundation on the newest cutting edge technology in the field of bonding and nanohybrides, which I build my clinical cases upon, I am going to show-case different approaches, to chair-side treatments in restorative dentistry. Various techniques, with various composite materials are going to be elaborated upon, with references to the newest of research in the aforementioned field. Everything from direct composite restorations using silicon stamps to a chair-side-preparation of indirect restorations, using die silicone. Furthermore the use of cutting edge materials, being nanohybrid-composites and bundled glass-fiber-posts are going to be examplified, to give a taste of what the future looks like for the respectable field of restorative dentistry.
Keynote Forum
Vanishree
SEGi University, Malaysia
Keynote: Comparative assessment of pH and ion diffusion rates from three different cavity liners
Time : 10:00-10:30

Biography:
Abstract:
Keynote Forum
Vibha Singh
Keynote: Evaluation of herbal preparation in management of oral submucous fibrosis
Time : 10:30-11:00

Biography:
Vibha Singh is currently working as Professor in the Department of Oral and Maxillofacial Surgery K.G.M.U, Lucknow India. She has completed her Graduation and Post-graduation from the same institute. She has published more than 90 scientific paper and presented scientific paper in national and international conferences and also serving as Editorial Board Member of several journals.
Abstract:
Introduction & Objective: Oral sub mucous fibrosis is a chronic debilitating disease and a well-recognized potentially premalignant condition of the oral cavity, various medical and surgical modalities have been used but results are not satisfactory owing to recurrence, adverse effects and some worsening condition. Thus analyzing the disease condition, OSMF can be considered as Vata Pitta dominant Tridosha Chronic Sarvasara Mukharoga (disease affecting the whole oral cavity) and it is obvious that it needs to be treated at local as well as systemic level. The objective is to evaluate the role of an herbal preparation in the Grade-I and Grade-II and recalcitrant cases of oral submucous fibrosis and its consequent improvement in trismus and mouth opening and reduction in burning sensation; to assess the changes in the levels of serum IL-6 and serum antioxidants after administration of the preparation both topically and systemically.
Method: The study comprised of minimum 30 patients having OSMF aged from 16 and up to 60 years attending the OPD of Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, King George's Medical University, Lucknow. The patients were enrolled in the study irrespective of sex, caste and creed. An informed consent was being taken from the patient. It was an open-label randomized clinical trial comprising of holistic Ayurvedic approach a clinical trial comprised of 30 patients of clinically diagnosed cases of OSMF. Herbal preparation was made and given to the patients for oral rinse and gargle for 3-5 minutes twice a day for 4 months.
Results: Clinical evaluation was done every 15 days. Pre and post interventional evaluation of biochemical parameter, serum antioxidant, IL6 was done and was marked improvement in clinical as well as biochemical parameters.
Conclusion: The herbal preparations are very effective in management of early stage of submucous fibrosis as well for the prevention of the submucous fibrosis which is very common in our country and potential pre malignant lesion.
- Orthodontics
Location: Hall-1

Chair
James D. Bates
American Board-Certified Oral And Maxillofacial Surgeon , USA

Co-Chair
Oscar Malaguti
Mr. Face Odontostomatological Clinic, Italy
Session Introduction
Meisha Gul
Aga Khan University Hospital Karachi, Pakistan
Title: Most effective method for the management of physiologic gingival hyperpigmentation: A systematic review and metaanalysis
Time : 11:30-12:00
Biography:
Meisha Gul done bachelors in Dental Surgery (BDS) from Karachi Medical and Dental College, Karachi, Pakistan in year 2012 and now enrolled in Post-graduation (FCPS Operative Dentistry) from Aga Khan University Hospital Karachi, Pakistan from 2016- present.
My fields of research include Endodontics, Periodontology, Restorative dentistry and prosthodontics. I have published multiple research papers both in national and international peer reviewed journals and working on multiple new research projects. I have also presented my research in national and international forums.
Abstract:
Introduction & Aim: Gingival color is an important component of an attractive smile. It helps to increase once self-confidence and reflect positive impact on the viewers. The aim of the present study was to identify most effective treatment option for the management of generalized physiological gingival hyperpigmentation.
Method: A thorough literature search was done from 1919 to October 2018 on different databases (CINHAL, PubMed and Dental and Oral Science) and manual search was also conducted to answer the review question. Only clinical trials done on human subjects and focused on different depigmentation methods were included. Control group in all the included studies was surgical stripping. The outcome was the amount of recurrence and discomfort associated. Final selected 25 articles underwent qualitative analysis and few studies underwent meta-analysis. RevMan software was used for data analysis.
Results: Out of total 26,132 articles, 25 met the inclusion criteria. Laser ablation was the most frequently used method for depigmentation in the included studies. There was no significant difference in terms of amount of depigmentation achieved (P=0.23) and recurrence between the groups (P=0.75). However, laser ablation was associated with significantly less post-operative pain when compared to surgical stripping group (P≤ 0.05).
Conclusion: All gingival depigmentation techniques are equally effective. Diode laser was the most frequently used method for depigmentation and associated with less discomfort and pain more patient preference and satisfaction. More good quality evidence in form of Randomized control trials are needed to draw strong conclusion.
Meisha Gul
Aga Khan University Hospital Karachi, Pakistan
Title: Most effective method for the management of physiologic gingival hyperpigmentation: A systematic review and metaanalysis
Biography:
Meisha Gul done bachelors in Dental Surgery (BDS) from Karachi Medical and Dental College, Karachi, Pakistan in year 2012 and now enrolled in Post-graduation (FCPS Operative Dentistry) from Aga Khan University Hospital Karachi, Pakistan from 2016- present.
My fields of research include Endodontics, Periodontology, Restorative dentistry and prosthodontics. I have published multiple research papers both in national and international peer reviewed journals and working on multiple new research projects. I have also presented my research in national and international forums.
Abstract:
Introduction & Aim: Gingival color is an important component of an attractive smile. It helps to increase once self-confidence and reflect positive impact on the viewers. The aim of the present study was to identify most effective treatment option for the management of generalized physiological gingival hyperpigmentation.
Method: A thorough literature search was done from 1919 to October 2018 on different databases (CINHAL, PubMed and Dental and Oral Science) and manual search was also conducted to answer the review question. Only clinical trials done on human subjects and focused on different depigmentation methods were included. Control group in all the included studies was surgical stripping. The outcome was the amount of recurrence and discomfort associated. Final selected 25 articles underwent qualitative analysis and few studies underwent meta-analysis. RevMan software was used for data analysis.
Results: Out of total 26,132 articles, 25 met the inclusion criteria. Laser ablation was the most frequently used method for depigmentation in the included studies. There was no significant difference in terms of amount of depigmentation achieved (P=0.23) and recurrence between the groups (P=0.75). However, laser ablation was associated with significantly less post-operative pain when compared to surgical stripping group (P≤ 0.05).
Conclusion: All gingival depigmentation techniques are equally effective. Diode laser was the most frequently used method for depigmentation and associated with less discomfort and pain more patient preference and satisfaction. More good quality evidence in form of Randomized control trials are needed to draw strong conclusion.
Vanishree
SEGi University, Malaysia
Title: Comparative assessment of pH and ion diffusion rates from three different cavity liners

Biography:
Vanishree has completed her Masters in Pediatrics Dentistry from Rajiv Gandhi University of Health Sciences, India. She is currently working as a Lecturer at SEGi University, Kota Damansara, Malaysia. She has published more than 20 papers in reputed journals.
Abstract:
Cavity liners are film-forming materials which are applied in a thin layer to seal the dentine and walls of the cavity against the influx of bacteria or irritants from restorative procedures. Cavity liners are pulp protection materials placed with minimal thickness which act as cavity sealers and provide beneficial functions, such as fluoride release, adhesion to tooth structure with antibacterial action that promotes the health of the pulp. Several materials have been used as sealers, such as, glass ionomer cement, resin modified glass ionomer cement and calcium hydroxide. The newer materials, mineral trioxide
aggregate and biodentine are also used to protect the pulp. Biodentin is a promising material and has the potential of making major contributions in the field of dentistry. We have compared and assessed the pH and diffusion of ions from three different materials when used as a cavity liner in permanent molars. A standard class-I cavity preparation was made in 30 extracted permanent molars with maintaining remaining dentin thickness of 1±0.3 mm tissue. Samples were divided into three equal groups for three different materials and two teeth as positive controls. Indirect pulp capping was performed in all the teeth by using Dycal, light curing calcium hydroxide (Pulpdent) and Biodentin. The leached Ca2+ ions were measured using optical emission spectrometry and the release of OH– ions using a pH meter. The measurements were performed after 24 hours, 7 days and 28 days in saline solution. Samples were subjected for statistical analysis by using ANOVA test.
Vibha Singh
King George Medical University, India
Title: Evaluation of herbal preparation in management of oral submucous fibrosis

Biography:
Vibha Singh is currently working as Professor in the Department of Oral and Maxillofacial Surgery K.G.M.U, Lucknow India. She has completed her Graduation and Post-graduation from the same institute. She has published more than 90 scientific paper and presented scientific paper in national and international conferences and also serving as Editorial Board Member of several journals.
Abstract:
Introduction & Objective: Oral sub mucous fibrosis is a chronic debilitating disease and a well-recognized potentially premalignant condition of the oral cavity, various medical and surgical modalities have been used but results are not satisfactory owing to recurrence, adverse effects and some worsening condition. Thus analyzing the disease condition, OSMF can be considered as Vata Pitta dominant Tridosha Chronic Sarvasara Mukharoga (disease affecting the whole oral cavity) and it is obvious that it needs to be treated at local as well as systemic level. The objective is to evaluate the role of an herbal preparationin the Grade-I and Grade-II and recalcitrant cases of oral submucous fibrosis and its consequent improvement in trismus and mouth opening and reduction in burning sensation; to assess the changes in the levels of serum IL-6 and serum antioxidantsafter administration of the preparation both topically and systemically.
Meisha Gul
Aga Khan University Hospital Karachi, Pakistan
Title: Most effective method for the management of physiologic gingival hyperpigmentation: A systematic review and metaanalysis

Biography:
Meisha Gul done bachelors in Dental Surgery (BDS) from Karachi Medical and Dental College, Karachi, Pakistan in year 2012 and now enrolled in Post-graduation (FCPS Operative Dentistry) from Aga Khan University Hospital Karachi, Pakistan from 2016- present.
Abstract:
Introduction & Aim: Gingival color is an important component of an attractive smile. It helps to increase once self-confidence and reflect positive impact on the viewers. The aim of the present study was to identify most effective treatment option for the management of generalized physiological gingival hyperpigmentation.
Method: A thorough literature search was done from 1919 to October 2018 on different databases (CINHAL, PubMed and Dental and Oral Science) and manual search was also conducted to answer the review question. Only clinical trials done on human subjects and focused on different depigmentation methods were included. Control group in all the included studies was surgical stripping. The outcome was the amount of recurrence and discomfort associated. Final selected 25 articles underwent qualitative analysis and few studies underwent meta-analysis. RevMan software was used for data analysis.
Meelaashah
Universitas Padjadjaran, Indonesia
Title: Prevalence of tongue lesions among dental students in faculty of dentistry universitas padjadjaran

Biography:
Meelaashah is currently pursuing her Dental Education at University of Padjadjaran, Indonesia. She has completed her Sarjana Kedokteran Gigi (SKG) which is the first degree before entering the clinical practice. She has completed her research in Oral Medicine titled “Prevalence of Tongue Lesions among Dental Studentsin Faculty of Dentistry Universitas Padjadjaran”.
Abstract:
Introduction & Objective: There are various lesions can be found on the surface of the tongue. Around the globe, many researches have conducted to observe the condition of the tongue lesions but not in Indonesia that focuses on dental students. This research study is carried out to obtain the prevalence of tongue lesions among dental students in Faculty of Dentistry Universitas Padjadjaran.
Method: The study used descriptive method and total sampling. The research was conducted on 250 clinical dental students in Rumah Sakit Gigi dan Mulut Unpad. Tongue lesions were examined and the data were recorded. The data were presented with simple frequency distribution table.
Sarah Irfan and Mubassar Fida
The Aga Khan University Hospital, Karachi, Pakistan
Title: Association of symmetric and asymmetric orthodontic extractions with different occlusal characteristics

Biography:
Sarah Irfan did her bachelors in Dental Surgery from Khyber College of Dentistry, Peshawar, Pakistan in year 2012 and is now enrolled in Orthodontic Residency
Program at The Aga Khan University Hospital, Karachi, Pakistan since 2016. Her fields of research include Orthodontics and Periodontology. She has worked on
multiple research projects and have presented her researches in both national and international forums.
Abstract:
Different extraction patterns are employed during orthodontic treatment. The aim of this study was to compare occlusal parameters in symmetric and asymmetric extraction groups that led to the decision of certain extraction pattern. This will help in developing accurate treatment plans in the future which will improve both the efficiency and outcome of the treatment.
A cross-sectional study was conducted using orthodontic files of 62 patients at a tertiary care hospital. These patients were divided into two groups according to their treatment approach. Group 1 and Group 2 consisted of 31 patients each treated with symmetric and asymmetric extraction patterns respectively. Categorical variables such as gender, and canine and molar relationships were reported as frequencies and percentages. The frequencies of canine and molar relationships were compared between the symmetric and asymmetric extraction groups using Chi-square test. The mean midline discrepancy, overjet,
overbite, and tooth material-arch length discrepancy were compared between the two groups using independent sample t-test. A p-value < 0.05 was taken as statistically significant. Greater overjet values were found in the symmetric extraction group, whereas greater values of midline discrepancy were found in the asymmetric extraction group. Molar and canine relationship also showed significantly different values between the symmetric and asymmetric groups. It can be concluded that overjet, midline discrepancies, molar and canine relationships play an important role in formulating ideal extraction plans. Customized treatment plans on the basis of comprehensive analysis should be developed to expect reliable results.

Biography:
Omid Panahi has graduated from Centro Escolar University in field of Doctor of Dental Medicine (DMD) and MSc Oral and Maxillofacial Surgery at Yeditepe
University, Istanbul, turkey. He has published more than 40 papers in reputed journals and has been serving as an Editorial Board Member of ISI journals.
Abstract:
Nanotechnology based dentistry comprises the areas of expertise like diagnosis, materials, restorative dentistry and surgery. Manipulating nanotechnology in each of these fields reveals extensive advantages. In this study, the merits which have been presented by nanotechnology in dentistry have been highlighted. By nano-diagnostics based on nanostructures, detection of diseases like tumor cells in initial stages have been possible which was not possible in chemical-based diagnostic techniques. Nano dental materials have two main features, strength and esthetics. Artificial teeth and dental implant with better quality are available based on nanomaterials. In nano surgeries the main goal is performing surgery at cellular levels. Nano dentistry as a multidisciplinary field of study has gained great interest in the past decade which leads to fast growth of this field with noticeable benefits for dentists and patients.
Kamil Zafar
Aga Khan University Hospital, Pakistan
Title: Success of pulpotomy in mature permanent teeth with irreversible pulpitis: A systematic review

Biography:
Kamil Zafar has completed his BDS from Dr. Ishrat-ul-Ibad Institute of Oral Health Sciences, Dow University of Health Sciences. He is currently a Post-graduate Trainee in the section of Operative Dentistry at the Aga Khan University Hospital. He has published four to five papers in reputed journals and has been working on several research projects.
Abstract:
The objective of present systematic review is to evaluate the success of pulpotomy in mature permanent teeth presented with irreversible pulpitis. The following databases were searched: PubMed, Oral and Dentistry Database, Cochrane and CINAHL plus. We included studies published in English language only. However narrative reviews and case reports/series were excluded. The first electronic and hand search yielded a total of 2851 articles. After going through extensive screening and eligibility process, only 6 articles were finally selected for the review. The follow-up period ranged from 1-10 years. Randomized controlled trial compared pulpotomy with the root canal treatment and reported comparable and even better success of the pulpotomy (78% success). All the other studies have also shown better clinical and radiographic success of pulpotomy (68%- 100%). Pulpotomy can be considered as an alternative option for mature permanent teeth with irreversible pulpitis.
Dyah Setyorini
Faculty of Dentistry University of Jember, Indonesia
Title: The Ability Pacar Air Stem (Impatiens balsamina Linn) Etanol Extract as Antibacterial Against of of Streptococcus mutans
Time : 11:30-12:00

Biography:
Dyah Setyorini has completed her Magister Program at the age of 13 years from Airlangga University. She is the xice dean of Faculty of Dentistry University of Jember, Indonesia. She has published more than 10 papers in reputed journals.
Abstract:
Background:The Prevalence of dental and oral diseases in Indonesia is stil categorized asl high. In 2007,it reached to 23.5%, and and even increased to 25.9% by 2013. The dominant dental and oral disease suffered was caries which has prevalence of 43.4%. Dental caries is an infectious disease that is progressive and accumulative in tooth tissue. The main bacteria that cause caries is Streptococcus mutans. Herbal plants can be used as an alternative in preventing the growth of bacterial colonies, one of which is with the balsam plant stem extract. Balsam plant stem extract contain naphthaquinone, kaempferol, quercetin, alkaloid, terpenoid, and phenol suspected to be antibacterial. Objective: to determine the inhibition of balsam plant stem extract on the growth of Streptococcus mutans. Methods: well diffusion method with 6 samples in each study group. The study group consisted of 4 treatment groups (6.25%, 12.5%, 25%, and 50% balsam plant stem extract), positive control group (povidone iodine), and negative control group (aquadest). Data were analyzed using Kruskal Wallis and Mann-Whithney test. Results and conclusions: balsam plant stem extract of 12.5%, 25%, and 50% concentrations have a higher inhibitory power than povidone iodine. Balsam plant stem extract has ability as antibacterial to Streptococcus mutans.
Sri Hernawati
Faculty of Dentistry University of Jember, Indonesia
Title: The mechanism of pomegranate extract (Pumica granatum L) in killing oral cavity cancer cells through VEGF expression and apoptosis
Time : 12:00-12:30

Biography:
Sri Hernawati has completed her PhD at the age of .... years from Airlangga University. She is the xice dean of Faculty of Dentistry University of Jember, Indonesia. She has published more than 10 papers in reputed journals.
Abstract:
Cancer is one of the leading causes of death throughout the world. In 2013, it was the number seven cause of death In Indonesia, by reaching 1.4% or an estimated 347,792 people. Among them, squamous cell carcinoma is the most common cancer in the oral cavity, patient survival is less than 50 %. Despite rapid advances in the field of surgical therapy, radiation, and chemotherapy, the treatment of cancer has not been completed. Meanwhile, new cases continue to emerge every year. The development and growth of cancer cells is caused by several factors, including; Apoptotic barriers and angiogenesis activity. The formation of angiogenesis is induced by growth factors, one of which is dominated by VEGF. With these backgrounds, authors want to inhibit cancer cell growth by increasing apoptosis of cancer cells and inhibiting the formation of angiogenesis. Pomegranate (punica granatum L, PGL) is one of the plants that has an active ingredient of ellagic acid (EA), EA in some studies has anti-cancer activity in vitro, but EA is difficult to absorb. Biovability of pomegranate / PGL fruit extract is better than EA because it is easily absorbed and contains polyphenol. The aim of this study was to determine the mechanism of action of whole pomegranate extract (PGL) in killing oral cavity cancer cells through VEGF expression and apoptosis. The research method used was experimental laboratories, 24 mice (Balb / c), males, aged 5 months were divided randomly into 3 groups: K0 (not suffering from cancer and not given PGL), K1 (had cancer and was not given PGL, P1 (have cancer and is given PGL). Mice become cancerous by: injecting the buccal mucosa of the right mouse with benzopirene 0.04 mg dissolved in 0.04ml olivarum oil, 3 times a week for 4 weeks. Giving PGL at a dose of 75 mg / kg BW / day for 4 weeks. Examination using immunohistochemistry and tunnel assay techniques. The results showed that administration of pomegranate whole extract (PGL) group P1 could kill cancer cells by decreasing VEGF expression 0.183 ± 0.098 compared to KO group 0.133 ± 0.103 did not differ significantly, differ significantly in comparison with K1 group 0.350 ± 0.104. Whole pomegranate extract (P1) killed cancer cells by increasing apoptosis expression highest 0.367 ± 0.196 compared to the KO group 0.083 ± 0.132 and K1 0.050 ± 0.054 significantly different than KO and K1. In conclusion, the mechanism of action of pomegranate extract (PGL) / P1 in killing cancer cethlls is by increasing apoptosis expression and decreasing VEGF expression
Biography:
Abstract:
Background: Dental caries are a global public health problem and influence the overall health of children. The risk factors for caries include biological, socio-behavioral and environmental factors. This cross-sectional study assessed dental caries and their associations with socioeconomic factors, oral hygiene practices and eating habits among Emirati and non-Emirati children in Abu Dhabi, United Arab Emirates (UAE).
Methods: The stratified sample comprised children aged 18 months to 4 yearsrecruited from 7 nurseries. The World Health Organization (WHO) decayed, missing and filled teeth index (dmft) was used to analyze the dental status of the children. Parents completed a questionnaire regarding demographics, food consumption and oral habits. The study was approved by the Research Ethics Committee at Zayed University, UAE.
Results: A total of 186 children with a mean age of 2.46 years, of which 46.2% were Emirati, participated. Overall, 41% of the children had dental caries. The mean dmft±SD was 1.70±2.81 with a mean±SD decayed component (dt) of 1.68±2.80 and mean±SD filled component (ft) of 0.02±0.19. Emirati children showed higher mean dmft, Plaque Index and Significant Carries Index values than non-Emirati children (P<0.000). Low maternal education, rural nursery location, infrequent tooth-brushing, frequent consumption of high-sugar food items and Emirati nationality were factors significantly associated with dental caries.
Conclusions: In this study, 4 out of 10 nursery children were found to have dental caries. Sociodemographic factors, dietary and oral health habits were associated with dental caries. Effective oral health interventions tailored to improve eating habits and the dental screening of children in this age group are imperative to mitigate these concerns.
Biography:
Dr. Nadiyeh A.Azar graduated in general dentistry in Tabriz university of iran .He is a partner Dr.roghayeh Jahanjoo and he worked on this study for 5 years and after surgery on 72 patients, he have enormous results.so he would like to share it to dental medicine community. Also he should to inform you that he had patent registration for this study and he have primary application number from WIPO.
Abstract:
The Invention of absorbable scaffold containing a slow-release lidocaine drug is a medical means in the form of a pad or lidocaine-saturated scaffold which is placed in the operation field at end of molar tooth surgery before it's sutured. Slow-release lidocaine (with a particular formula) starts being released in 48 to 72 hours and surgicel pad which has been used as the scaffold starts being absorbed in the body after two weeks. This gets patient feel the pain with more less intensity and in a short period of time during gradual release of drug.
- Oral Pathology
Location: Hall-1

Chair
James D. Bates
American Board-Certified Oral And Maxillofacial Surgeon , USA

Co-Chair
Oscar Malaguti
Mr. Face Odontostomatological Clinic, Italy
Session Introduction
H. Nazar
Ministry of Health, Kuwait
Title: Oral cancer knowledge among new dental graduates
Biography:
Dr. Huda Nazar has completed her BDS in 1994 from Cairo University in Egypt and completed CAGS, MSD, and American Written Board Examination in Dental Public Health in 2010 from Boston University- MA,USA. She is Head of Research and Survey Division since 2014, Dental Administration-MOH-Kuwait. She has several published papers.
Abstract:
Background: Early detection of oral cancer can improve the prognosis and the 5-year survival rate. Oral cancer screening should be done by dentists as a routine procedure.
Objectives: To assess the level of oral cancer knowledge among new dental graduates who attended the continuing education courses through MOH, Dental Administration –Kuwait. Methods: Self-reporting questionnaire was distributed to newly graduated dentists in Kuwait during 2012 to 2015. The questionnaire included questions on knowledge, practices, opinion, and attitude regarding oral cancer. The answers to knowledge questions were coded, then entered, and analyzed separately using Epi-Info 3.5.3. Results: Of the 310 dentists who responded, 96% were Kuwaiti, 4% were from other countries. The mean age was 31.7±10.3 years with the gender distribution of 55.2% males and 44.8% females. The mean experience was 1.4±1.8 years. Ninety four percent of the dentists had a bachelor degree and 6% had degrees more than bachelor. Majority of dentists knew the lesions associated with oral cancer (92%). Also, most of dentists had knowledge about the characteristics of oral cancer metastases (83%) as well as its common risk factors (95%). Their knowledge on the age of oral cancer diagnosis (41%) as well as its common symptoms (51%) was not very encouraging. Almost, all dentists were interested in attending continuing education courses regarding oral cancer (96%). Conclusion: Most dentists showed a good knowledge about various aspects of oral cancer. More continuing education programs should be arranged to train newly graduated dentists regarding visual oral cancer screening. Oral cancer screening should be a routine procedure for the high risk patients at the primary oral health care clinics. Key words: oral cancer, dentists, knowledge, risk factors.